Genomic Instability
Genomic instability refers to the gradual accumulation of cellular changes over time, influenced by factors such as UV exposure, environmental stressors, and normal metabolic processes. These changes can impact various aspects of skin and overall health.
This process affects women’s bodies by:
- Contributing to visible signs of aging, including changes in skin texture, elasticity, and firmness.
- Affecting collagen and elastin function, which helps maintain skin smoothness and resilience.
- Impacting mitochondrial efficiency, which may influence energy levels and overall vitality.
- Playing a role in immune function and inflammatory responses, which are important for long-term well-being.
Supplements
Key Ingredients
- Resveratrol, Quercetin, Zinc – Support antioxidant defenses, contributing to skin and cellular health.
- NAD Precursors – Help maintain cellular energy production and support natural skin resilience.
Lontreau Supplements
- EPA/DHA – Helps support skin hydration and overall wellness.
- BioCsynergy – An anti oxidant blend designed to provide antioxidant support.
Skincare Recommendations
- Use a chemical-free, mineral-based sunscreen daily to protect the skin from UV-induced oxidative stress, collagen breakdown, and premature aging.
- Minimize exposure to environmental pollutants, which can impact skin quality and resilience by increasing oxidative stress.
- Incorporate skincare products with antioxidant and soothing ingredients to help reduce the effects of environmental stressors and support barrier health.
- Apply antioxidant-rich serums such as Game Changer to help support skin’s natural defenses.
Key Skincare Ingredients
- TEX (Tomato Extract) – Contains naturally occurring antioxidants that help support an even skin tone and enhance radiance
- BEV (Bio Identical Vegan Elastin) - A biodesigned, 100% vegan elastin that mimics human elastin to support skin elasticity, hydration, and resilience.
- REX - An antioxidant-rich ingredient that helps protect the skin from pollution, blue light, and environmental stressors while supporting its natural defense and repair mechanisms.
Lifestyle Recommendations
- Practice comprehensive sun protection, including wearing protective clothing and seeking shade when outdoors, to help minimize environmental stressors that contribute to skin aging.
- Engage in regular exercise, which plays a role in overall health and well-being, supporting circulation and cellular function.
- Use at-home red light therapy devices like LightStim to help support skin rejuvenation, collagen production, and overall skin vitality.
- Have a NAD boosting IV treatment
- Incorporate nutrient-dense foods rich in polyphenols, flavonoids, and antioxidants, such as dark leafy greens, berries, cruciferous vegetables, and omega-3-rich foods.
Telomere Attrition
Telomeres are protective caps at the ends of our chromosomes, similar to the plastic tips on shoelaces. They shorten with each cell division, eventually leading to cellular senescence. This process impacts women's health by:
- Affecting the regenerative capacity of skin, potentially accelerating the appearance of fine lines and wrinkles
- Influencing bone density and joint health as cellular renewal slows down
- Potentially impacting reproductive health and hormonal balance
What you can do
Supplement Recommendations:
- Ingredients: Astragalus extract, omega-3 fatty acids, and vitamin D
- Lontreau supplements: EPA/DHA, Vitamin D
Skincare Recommendations
- Use retinol-based products to stimulate cellular turnover
- Apply peptide-rich creams to support collagen production
- Incorporate niacinamide-containing products to improve skin barrier function
Lifestyle Recommendations
- Manage stress through meditation or mindfulness practices to potentially slow telomere attrition
- Maintain a consistent sleep schedule for optimal cellular repair and telomere maintenance
- Incorporate regular cardiovascular exercise to support overall cellular health
Epigenetic Alterations
Epigenetic changes involve modifications to gene expression without altering the DNA sequence itself. These changes can accumulate over time, leading to altered gene activity and cellular function.
What you can do
Supplement Recommendations
- Ingredients: Curcumin, green tea extract, and folate
- Lontreau supplements: BioCsynergy, Greens antioxidants powder
Skincare Recommendations
- Use products containing epigenetic regulators like sirtuins or resveratrol
- Apply topical antioxidants to protect against environmental stressors.
- Incorporate products with DNA methylation modulators
Lifestyle Recommendations
- Adopt a plant-based diet rich in polyphenols and antioxidants
- Practice intermittent fasting to promote cellular rejuvenation
- Engage in regular mental stimulation through learning new skills
Loss of Proteostasis
Loss of proteostasis refers to the decline in the body's ability to maintain protein quality and function, leading to the accumulation of damaged proteins.
What you can do
Supplement Recommendations
- Ingredients: Quercetin, resveratrol, and N-acetyl cysteine
- Lontreau supplements: BioCsynergy, NAC
Skincare Recommendations
- Use products containing chaperone proteins to support proper protein folding
- Apply creams with proteasome activators to enhance protein degradation
- Incorporate products with autophagy-inducing ingredients
Lifestyle Recommendations
- Incorporate regular strength training to stimulate protein synthesis
- Ensure adequate protein intake from diverse sources
- Practice heat exposure through saunas or hot baths to activate heat shock proteins
Deregulated Nutrient Sensing
Deregulated nutrient sensing occurs when the body's ability to detect and respond to nutrient levels becomes impaired. This hallmark of aging affects metabolism and energy production, leading to metabolic imbalances and accelerated aging.
What you can do
Supplement Recommendations
- Ingredients: Berberine, chromium, and alpha-lipoic acid
- Lontreau supplements: EPA/DHA, BioCsynergy
Skincare Recommendations
- Use products containing epigenetic regulators like sirtuins or resveratrol
- Apply topical antioxidants to protect against environmental stressors
- Incorporate products with DNA methylation modulators
Lifestyle Recommendations
- Practice time-restricted eating to improve metabolic flexibility
- Engage in high-intensity interval training (HIIT) to enhance insulin sensitivity
- Minimize consumption of processed foods and added sugars
Mitochondrial Dysfunction
Mitochondrial dysfunction involves impaired energy production and increased oxidative stress, contributing to cellular aging and various age-related diseases.
What you can do
Supplement Recommendations
- Ingredients: Coenzyme Q10, PQQ, and L-carnitine
- Lontreau supplements: EPA/DHA, NAC
Skincare Recommendations
- Use products containing CoQ10 to support mitochondrial function
- Apply creams with antioxidants like vitamin C and E to combat oxidative stress
- Incorporate products that stimulate cellular energy production
Lifestyle Recommendations
- Engage in regular aerobic exercise to stimulate mitochondrial biogenesis
- Practice cold exposure through cold showers or cryotherapy
- Optimize your sleep environment for quality rest and cellular repair
Cellular Senescence
Cellular senescence refers to the accumulation of non-dividing, dysfunctional cells that promote inflammation and tissue degeneration.
What you can do
Supplement Recommendations
- Ingredients: Fisetin, quercetin, and apigenin
- Lontreau supplements: BioCsynergy, NAC
Skincare Recommendations
- Use products containing senolytic compounds to target senescent cells
- Apply creams with growth factors to support cellular regeneration
- Incorporate products that stimulate collagen production
Lifestyle Recommendations
- Maintain a consistent exercise routine to promote cellular turnover
- Practice stress reduction techniques to minimize chronic stress
- Ensure adequate hydration to support cellular function and waste removal
Stem Cell Exhaustion
Stem cell exhaustion involves the decline in the regenerative potential of tissues due to stem cell depletion or dysfunction.
What you can do
Supplement Recommendations
- Ingredients: Ginseng extract, blueberry extract, and L-carnosine
- Lontreau supplements: EPA/DHA, Collagen
Skincare Recommendations
- Use products containing plant stem cell extracts to support skin regeneration
- Apply creams with peptides to stimulate collagen production
- Incorporate products that support the skin's natural renewal process
Lifestyle Recommendations
- Engage in regular moderate-intensity exercise to stimulate stem cell activation
- Practice intermittent fasting to promote stem cell regeneration
- Ensure adequate sleep for optimal stem cell function and tissue repair
Altered Intercellular Communication
Altered intercellular communication refers to changes in signaling between cells, leading to chronic inflammation and impaired tissue function.
What you can do
Supplement Recommendations
- Ingredients: Omega-3 fatty acids, curcumin, and resveratrol
- Lontreau supplements: EPA/DHA, BioCsynergy
Skincare Recommendations
- Use products containing anti-inflammatory ingredients like niacinamide
- Apply creams with ceramides to support skin barrier function
- Incorporate products that promote cellular communication and renewal
Lifestyle Recommendations
- Cultivate strong social connections to support overall health
- Practice mindfulness meditation to reduce stress and inflammation
- Engage in regular outdoor activities for exposure to natural light and fresh air
Chronic Inflammation
Chronic inflammation, also known as "inflammaging," is a state of low-grade, persistent inflammation that occurs with aging without overt infection. This hallmark significantly impacts overall health and longevity.
What you can do
Supplement Recommendations
- Ingredients: Omega-3 fatty acids, curcumin, and resveratrol
- Lontreau supplements: EPA/DHA, BioCsynergy
Skincare Recommendations
- Use products containing anti-inflammatory ingredients like niacinamide
- Apply creams with ceramides to support skin barrier function
- Incorporate products that promote cellular communication and renewal
Lifestyle Recommendations
- Adopt an anti-inflammatory diet rich in whole foods and omega-3s
- Practice regular low-impact exercises like yoga or swimming
- Engage in stress-reduction techniques such as meditation or deep breathing exercises
Disabled Macroautophagy
Macroautophagy is a cellular recycling process that declines with age, leading to the accumulation of cellular waste and dysfunction.
What you can do
Supplement Recommendations
- Ingredients: Spermidine, resveratrol, and quercetin
- Lontreau supplements: BioCsynergy, NAC
Skincare Recommendations
- Use products containing autophagy-inducing ingredients like resveratrol
- Apply serums with peptides to support cellular renewal
- Incorporate products that stimulate collagen production and skin repair
Lifestyle Recommendations
- Practice intermittent fasting to promote autophagy
- Engage in regular exercise, particularly resistance training
- Ensure adequate sleep for optimal cellular repair processes
Dysbiosis
Dysbiosis refers to an imbalance in the gut microbiome, which can significantly impact overall health and contribute to aging.
What you can do
Supplement Recommendations
- Ingredients: Probiotics, prebiotics, and polyphenols
- Lontreau supplements: Starch resistance fibre/gut health, Greens antioxidants powder
Skincare Recommendations
- Use products containing prebiotics to support skin microbiome
- Apply creams with postbiotics to enhance skin barrier function
- Incorporate products that balance skin pH and support a healthy skin ecosystem
Lifestyle Recommendations
- Consume a diverse range of plant-based foods to support microbiome diversity
- Minimize use of unnecessary antibiotics and harsh cleaning products
- Engage in regular physical activity to promote gut health
